INFORMATION ABOUT STEROIDS

NATURAL ANABOLIC STEROIDS

Anabolic-androgenic steroids are known as male hormones. The most important of these hormones is testosterone.

Testosterone is produced in the male testes (testicles). Is synthesized from cholesterol. Simplified principle of the regulation can be described as follows:

When testosterone levels fall below a given point (which is different for each individual) will diencephalon (HPA) secrete GnRH (gonadotrophin hormone Raeleasing). The action of the anterior pituitary gland (pineal gland) increases the production of LH (luteinizing hormone) and FSH (Follicle Stimulating Hormone). In men, LH stimulates the Leydig cells in the testes and stimulates the production of androgen hormones, ie. testosterone. FSH, together with testosterone stimulates the Sertoli cells in the testes that encourages the production and maturation of sperm. Sperm to properly matured, need to “swim” in testosterone.

Needless to talk about where “it” the most testosterone. The remaining testosterone is released into the bloodstream, where it absorbs 97-99% of the liver. The remaining percentage of free entry into the genital organs, but mainly in muscle cells, which under certain circumstances can promote muscle growth.

At this point already testosterone levels high and runs on the reverse process. Testosterone acts on the hypothalamus and suppresses the production of GnRH. Occurs also transform parts of testosterone to estrogen (female sex hormones). This feedback is used to maintain and regulate the levels of testosterone in the body.

This mechanism of action is called. the hypothalamic – pituitary – testes. For men aged 20-50 years is naturally produced on average 7 mg of testosterone per day. The amount of LH and FSH production is always the same, their relationships correlate with each other. Only a small portion of testosterone production causes muscle growth. Organism is programmed so that the sperm production is much more important than the increase in muscle, i.e. spermatogenesis is a priority. This process is repeated every 1-3 hours.

Effect of testosterone on the body:

 – supports protein metabolism and at the same time limiting their catabolism
 – stimulates the growth of target organs
 – stimulates spermatogenesis
 – contributes to male sexual characteristics (puberty supports the enlargement of the larynx and vocal amplification, supports typical body hair growth, increased secretion of sebaceous glands, increases muscle mass)
 – is closely related to the mental state of sexual desire, libido and aggression
 – has anabolic effects on muscle, bone and skin
 – closed epiphysis of long bones
 – affects the size of the seminiferous tubules and testicular
 – affects the psychological perception of reality and perspectives, particularly in relation  to the vision of the body identity and personality

In medical practice, the testosterone applied in a situation where the formation of abnormally low hormone patients. Also is indicated in the treatment of breast cancer in women. In large doses, it can have a positive impact on some life-threatening blood diseases. During puberty promotes growth in height and at the same time causing the development of male features of the (growth of body hair, voice, testicles, penis, skeletal muscles …).

SYNTHETIC ANABOLIC STEROIDS

Metabolic changes leading to the synthesis of proteins, fats and carbohydrates are referred to as anabolic. Their counterpart are marked catabolic mechanisms that are responsible for the breakdown and decomposition of complex structures such as proteins or fats. A healthy person always moves in a state of metabolic equilibrium, where the anabolic and catabolic processes in balance. AS is a substance whose structure is very similar to the male sex hormone testosterone and therefore may have an impact on the formation of tissues.

Synthetic AS have all been designed suitable modification of the testosterone molecule. This modification has been a number of different types that are to some extent different characteristics. Individual steroid preparations have a different relationship to the quality of androgenic (male characteristics highlighting) and anabolic (tissue growth promoting) effects. Efforts to suppress the androgen testosterone exposure resulted in the development and production of so-called. Anabolic steroids, which, however, never been to suppress androgenic properties. For example, some of the AS minimum support increases male characteristics (eg, Anavar), so that more women use. Unfortunately, these too do not support the AS or the formation of new tissue. This led to the conclusion that these two effects are indivisible.

Modification of testosterone helped create AS, which are processed by the body more slowly. If you take oral free testosterone (chemically modified) will be immediately absorbed by the liver. If you take it orally pass through the liver first, and then gets into skeletal muscle. Up to 98% of free testosterone is absorbed already in its first pass. Injected with free testosterone is first getting to the muscles and then to the liver. However, there is a 98% free testosterone is absorbed already in its first pass.

AS To be effective, they must be able to (before they become ineffective) several times to pass through the bloodstream. Modification testosterone molecule and adding elements group (alkyl group), a specific place (known as Alpha position – referred to as well as the position on the 17th carbon) have been created on the AS, which are heavier liver processor (Alpha-alkyl). AS based on this principle are able to pass through the liver several times and then become ineffective. This allows you to get AS to the muscles, causing there to have a desirable effect. But the liver is then forced to work much more. Most oral AS was created by a very similar way, therefore can cause liver failure.

Injecting AS are based on the base, so they are generally safer and usually present a danger to the liver. But some AS such. stanozolol (produced both in oral as well as injectable form) is chemically comparable to oral and therefore have the same effect (and unfortunately most undesirable).

The main role in the play AS injection of testosterone esters. Ester is a compound produced by the reaction between any fatty acid and alcohol (for AS is made esterification of steroid molecule at the position 17th carbon). Esterification of testosterone makes effective even if before the liver is absorbed, makes only one pass through the bloodstream. Most of the AS injection is administered intramuscularly, because the active substance reaches the muscle rather than the liver. These esters act longer and are safer than oral alpha-alkyl steroids.

The greater the number of carbon will have a fatty acid, the slower the release of steroid ester from the injection site in the muscle circulation and the longer the biological effectiveness of the injection preparation. Therefore can inject a long period. The most frequently used for the esterification are acid (names are in the form of acid salts):

 – propionate (3 carbons)
 – enanthate (7 carbons)
 – cypionate (8 carbons)
 – phenylpropionate (9 carbons)
 – decanoate (10 carbons)
 – undecanoate (11 carbons)
 – laurate (12 carbons)
 – hexyloxyfenylpropionát (15 carbons)

Few esters (eg methenolon acetate and testosterone undecanoate) can be administered orally. It is not entirely clear why methenolon acetate is also effective orally. Testosterone undecanoate enters the bloodstream through the lymphatic system and the liver, thus largely bypassing. These two esters are less burden on the liver than other oral steroids.

Anabolism of proteins leads to a reduction in excretion of urea (a waste product of protein metabolism) without changes in current excretion of uric acid, ammonia and nitrogen. Addition there is a reduction in urinary phosphate, chloride, calcium, sodium and potassium. But when he returns to normal nitrogen equilibrium, anabolic effect does not continue. At this point the phase degradation occurs.

Once stopped steroids, usually appears “feedback shock” accompanied by negative nitrogen balance and a significant decrease in body weight. The level of impact depends on the type of medication used, duration of administration, dosage, and their total physiological state of the individual.

PROCESSING OF ANABOLIC STEROIDS IN THE BODY

In order for steroids to work, must be contained and treated the cells. Anabolic steroid after transgressions membrane bound in the cell cytosol to a specific receptor, which is made up of protein. After activation complex hormone receptor is translocated complex in the nucleus, where it binds to the appropriate location chromatin and consequently there may be protein synthesis. Receptors have the ability to recognize AS, thus can bind steroid molecule and thus allow cells to process AS.

Under normal conditions, the receptors in skeletal muscle saturated molecules naturally produced testosterone. And why are “normal conditions” AS compounds only a minor effect on the growth and development of muscle strength. However, exercise increases the number of unsaturated receptors. It also increases the body’s ability to process AS, which also increases the effects of steroids at all. Steroid User must add heavy workout with a quality diet, or significant progress is achieved.

Women have more unsaturated receptors because they have lower levels of naturally produced testosterone. Therefore, they are also more susceptible to AS.

Regardless of the amount of training is the point where they are no longer all receptors in skeletal muscle saturated. If you’ve reached this point, further increase in benefits will never not bring the desired results. Unfortunately, these higher doses then saturates receptors in other parts of the body (prostate, heart, testes, …). It is the excess of such receptors, which cause different (malicious) AS physiological effect.

Testosterone is a naturally produced steroid, ie anabolic hormone forming tissue. Conversely, catabolic hormone cortisol is “destroying” the tissue. These two hormones continuously maintain tissue growth control. If the brain is found to be necessary tissue growth, start to increase the production of testosterone and decrease the production of cortisol. However, this process also works in reverse.

Steroids are the actors of strong muscle growth because they increase support two effective ways. AS matter of fact increase the rate of creation of new muscle cells and to block the effects of cortisol. Muscle cells contain receptors that are able to absorb molecules of different forms. AS and cortisol molecules are similar in form, so can take both AS receptors as well as cortisol. Hormone used to its effects, it must first get into the receptor. If any steroids used, the quantity of anabolic hormones circulating in the blood stream much greater than that of catabolic hormones and thus most receptors which they can be equipped with these hormones is already filled with molecules that have anabolic effects. Thus anabolic catabolic molecules will not allow access to the receptors and thereby increases the production of new muscle cells. This effect then exceeds the natural regulation of muscle growth.

But the whole thing is a catch!

The body continues to produce catabolic molecules, mostly in the form of cortisol. Cortisol levels are increasing because the molecules can not be processed at receptors that are already filled with molecules of AS. Levels of anabolic and catabolic molecules in the blood that balance. When releasing the receptor is the same then chances are once again filled anabolic or catabolic molecule. Finally receptors will contain half the anabolic and catabolic half molecules. At this point it is impossible to further muscle growth – has been achieved so plateau.

Bodybuilder whose growth has stopped, then it may decide to increase the dose of steroids so broke increasing cortisol levels in the blood. Unfortunately, this version offers only a temporary solution. This is because the additional salary is coming soon, and then a further increase in dose becomes absurd.

Some bodybuilders therefore decided not to risk their health by increasing doses and opt for immediate discontinuation. But the sudden interruption of the “shock therapy” should never commit! This fact leads to a crash when the catabolic molecules far beyond anabolic molecules. The bulk of the receptor molecule catabolic fill in a very short time it lost a significant amount of muscle.

Cortisol levels can be controlled using a pyramid scheme dosage. This system allows you to gain weight and also keep it real that you can balance the catabolic and anabolic processes in the body.

SIDE EFFECTS OF ANABOLIC STEROIDS  

 

CAUSES

Many reasons have been given as to why men and to a lesser degree, women choose to abuse steroids Among most abusers, it boils down to two simple concepts of performance and self-image. For over half a century, anabolic steroids have been used to enhance athletic ability.    Most often, the answer lies in a need to improve a particular type of performance. Whether the goal is an increase in physical size, strength, speed or stamina, in the mind of an abuser, it is a worthwhile endeavor, regardless of the risk.  Secondly, many abusers report a greater sense of fulfillment and a healthier self-image when taking steroids. Many young men report taking steroids simply because they want to look built, to emulate the bodybuilders they see in magazines, or even more importantly, to be more appealing to women. Moreover, a form of reverse anorexia seems to be prevalent in young males who are interested in fitness. The National Institute of Drug Abuse shows in recent studies that 325,000 teenage boys and 175,000 teenage girls are using steroids.  The number of adult abusers is even higher. (Consider that often, steroid abusers are private about their use and never report it. The actual number of abusers could be far greater.) The idea that they can never be big enough, fast enough or strong enough dominates their perception of self. Anabolic steroids would seem to be the answer to their prayers.

RATIONALE

Abusers can seem pretty well educated on the subject of their vice, however, the problem lies in the quality of the information. Most often, it’s hearsay or internet chatter, combined with a skewed rationale that explains away all the bad. Many abusers will tell you the doses they take aren’t harmful because they “cycle” (come off of steroids for a period of time and then begin again) or they only take a certain “good” steroid or not enough of a dose to harm them.  This couldn’t be further from the truth. When doctors prescribe steroids, it is generally to treat patients with a rare or specific disorder, and the drug is administered in the lowest possible dose as to minimize the negative side effects. But this isn’t about medicine; this is about unregulated, unsupervised abuse of a synthetic drug for the purpose of maximum muscle development and performance. Massive doses are required to achieve the results most abusers are looking for. When this is the case, there is no safe use.  In both cases of performance and image, abusers throw caution to the wind as their sense of achievement far outweighs their consideration of the enormous risks involved. Medical research shows steroid users subject themselves to over 70 side effects ranging in severity from liver cancer to acne, and include psychological as well as physical reactions. The liver and cardiovascular and reproductive systems are most seriously affected by steroid abuse. When discussing the powerful effects of anabolic steroids on the human body, we look at the short term effects, which can take from a few weeks to a few years to present themselves and the long term effects, some taking up to a decade or more to appear.

SHORT TERM SIDE EFFECTS

The short term, more immediate side effects of steroid abuse are a veritable buffet of problems. Let’s start with the men. Acne, testicular atrophy, decreased sperm count, gynecomastia (enlarged breasts in men), high blood pressure, increased LDL (bad) cholesterol, decreased HDL (good) cholesterol, fluid retention, abnormal liver function, and prostate enlargement, just to name a few.  Anabolic steroids can affect women differently than men, and in some cases, dramatically so. Women can experience many of the same dangerous effects as men including high blood pressure, high cholesterol, and liver damage. Many of the problems, however, are exclusively feminine representations of natural male characteristics such as male pattern balding, deepening of the voice, facial and body hair growth, and coarsening of the skin. For both sexes, increased aggressiveness, otherwise known as “roid rage,” commonly accompanies the use of steroids.  Now let’s break some of these down into further detail.

ACNE

One common side effect is the onset of acne or, in cases of adolescents where acne is already present, a much more severe case can present itself. The scientific explanation is quite colorful. Steroids enlarge the sebaceous glands in the skin. Then, they cause these glands to increase sebum (oil) production. The increased sebum leads to plug formation and serves as “food” for bacteria.  Normal hormones surge at puberty, which is why teens develop armpit and pubic hair, and why boys develop facial hair and deeper voices. This hormonal surge also contributes to the cause of acne in teens. Introducing steroids to this delicate balance is just asking for trouble.

SHRUNKEN TESTICLES

Testicular atrophy, a fancy term for shrunken balls, isn’t just a cosmetic problem. Because an outside source of testosterone is being introduced to the body, the testes no longer get the signal to produce their share. The brain is also being told to slow down the sperm factory, and that the body is getting sperm from an outside source, usually the hypodermic needle. The brain then sends a signal back to the testicles to take a break. This new function can cause temporary sterility, and the jury is still out on whether steroids are linked with permanent sterility or not. But why take the chance?

GYNECOMASTIA

Gynecomastia, a pretty word for man-boobs, is another not-so-good side effect of abuse that comes from the improper balance of testosterone. When the body converts the additional testosterone into estrogen and other female hormones in the male body, female breast tissue is sometimes formed. Often, surgery with a painful recovery time is the only method of removing the female tissue build-up. Basically, the surgeon enlarges the area to be liposuctioned with a large amount of sterile fluid then employs ultrasonic liposuction using sound waves to break up the fat. The surgery can cost upwards of $10,000 and you will be hard pressed to find insurance that will cover steroid abuse. 

HIGH BLOOD PRESSURE

The next effect on our list is high blood pressure, which is caused when the steroid forces the body to hold onto extra salt and water, rather than flushing it out as usual. Steroids also cause an increase in the body’s red blood cell count and hematocrit levels, resulting in higher blood pressure. The long term effects of high blood pressure are a list all their own. It causes the heart to get larger, which may lead to heart failure. Small bulges (aneurysms) can form in blood vessels, the main artery from the heart (aorta), arteries in the brain, legs, and intestines; and the artery leading to the spleen. Blood vessels in the kidney can narrow, which may cause kidney failure. Arteries throughout the body can “harden” faster, especially those in the heart, brain, kidneys, and legs. This can cause a heart attack, stroke, kidney failure or amputation of part of the leg. Blood vessels in the eyes may burst or bleed, which can cause vision changes and can result in blindness.   

HIGH CHOLESTEROL

High blood pressure is also often a result of high (LDL) bad cholesterol levels and/or low (HDL) good cholesterol levels. Steroids change the levels of lipoproteins that carry cholesterol in the blood. Steroids, particularly oral steroids, increase the level of low-density lipoprotein (LDL) and decrease the level of high-density lipoprotein (HDL). This increases the risk of atherosclerosis, a condition in which fatty substances are deposited inside arteries and disrupt blood flow. If blood is prevented from reaching the heart, the result can be a heart attack. If blood is prevented from reaching the brain, the result can be a stroke.

LIVER MALFUNCTION

Let’s move on to the liver, where just about everything you put in your body gets processed. In other words, just try to live without your liver. It won’t happen. Steroid abuse has been associated with liver tumors and a rare condition called peliosis hepatis, in which blood-filled cysts form in the liver. Both the tumors and the cysts can rupture, causing internal bleeding. Keep in mind, we’re talking short term effects. Long term liver effects, you don’t want to know, but we’ll get into that a little later.

ENLARGED PROSTATE

Next, the issue of prostate enlargement, which is a problem seen with aging males. This is not something you typically see in younger men, unless they’re taking anabolic steroids. Over the course of an average life span, the male prostate gland naturally grows thirty times its original size. It doesn’t need the help of additional testosterone to grow to the size of a grapefruit. However, when large amounts of synthetic testosterone are involved, the prostate grows faster. The long term effect of that is prostate cancer. It is medically proven that the cancer loves the taste of testosterone, which feeds the growth of cancer cells.

BALDING

Baldness in women steroid abusers is caused by the body’s confused over-production of DHT- a hair inhibitor enzyme, which generally affects both sexes similarly. Women see this change occurring first around the scalp line and can eventually cause balding that is irreversible.

MALE CHARACTERISTICS IN FEMALES

A deepening voice is another naturally male characteristic that can develop in women abusers simply because of the large amounts of testosterone sending male signals to the brain, the control room for hormone production, and the various glands that manage the hormone output. Steroids play havoc with the entire system.  Excess facial and body hair growth and coarse skin, both male characteristics, are unsavory by-products of steroid abuse by women caused by an overabundance of male hormones. While aggressiveness and heightened libido are side effects that can be experienced by both genders, some effects are uniquely female. For example, the enlarged or lengthened clitoris is inherently female as well as a confused and erratic menstrual cycle. Other traits may include shrinking breasts, anxiety, depression, and high levels of stress. All of these characteristics can be caused by introducing the amounts of synthetic steroids in the female body necessary to see a change in muscle development.

AGGRESSION

In both men and women steroid abusers, evidence of “roid rage” or increased aggression from too much testosterone is a hotly contested topic. However, in animal studies, the relationship between steroids and aggression has always been pretty clear. In some studies, more than 80 percent of steroid-treated animals become extremely aggressive. In humans, the picture has been clouded by alternative explanations and a lack of hard evidence. Only in recent years have researchers been able to confirm that steroid-induced aggression is a real human phenomenon that can occur in individuals who take large doses of steroids for extended periods of time. This heightened aggression can lead to irritability, stress, and violence.  When the circuits in the brain that are responsible for impulse control are influenced by steroids, it affects this system that inhibits aggressive response, predisposing some abusers to violent outbursts. Researchers do not yet know the key as to why some abusers are more affected than others, but the correlation between steroids and aggressive behavior is a documented phenomenon.

LONG TERM SIDE EFFECTS

Only in recent years have researchers been able to define the long term effects of steroid abuse. They are learning more each year as abusers age and problems present themselves. HIV One of the deadliest side effects, scoffed at by many abusers, is HIV. Intravenous needle sharing, combined with a heightened sex drive and libido function can be a very dangerous combination. This is especially true in adolescent teens and young adults who often have weaker decision-making skills and a high susceptibility to peer pressure. HIV and AIDS-related deaths are on the rise and the epidemic is not as popular in the media as in past decades. Most people adopt a “that stuff happens to other people” attitude, and many steroid abusers, already practiced rationalizers don’t even consider it at all.

LIVER FAILURE

Peliosis Hepatitis, a condition where blood-filled cysts replace liver and spleen tissue, has been reported in patients receiving long-term anabolic steroid treatments. These cysts have been associated with liver failure. Discontinued use of steroids has shown a regression and sometimes a complete disappearance of these cysts; however, during the course of steroid use, the cysts can create tumors. These tumors are less evident and can be silent until a life-threatening abdominal hemorrhage occurs.

CARDIOVASCULAR PROBLEMS

High blood cholesterol levels, as discussed earlier in this article, can lead to premature heart conditions, heart attacks and stroke. The increase in muscle mass can put undue strain on the rest of a body that is not prepared for the surprisingly fast new muscle development. The heart is put under more pressure to provide blood to more muscle tissue, while processing greater levels of bad cholesterol. Moreover, high blood pressure due to salt and water retention can put even further undue stress on the heart. No doubt, steroid abuse over long periods of time will inevitably cause damage.

STUNTED GROWTH

Studies have shown that adolescents who abuse steroids are at risk of being short for life. Because the body responds to puberty by slowing and eventually stopping growth, the pubescent period of life is crucial to future development. When the adolescent brain senses a certain level of hormones in the body, it will send messages to the bones to stop growing, closing the growth plates in the long bones. Young male abusers can expect to be permanently shorter than average height.

LIGAMENT AND JOINT INJURY

Steroids increase muscle mass and muscle strength, but they leave the joints and ligaments out of the equation. Steroid abusers can expect to eventually put too much strain on ligaments that cannot properly anchor the new muscle strength, leading to possibly severe injury and future surgery to correct torn shoulder joints or knee ligaments. The muscles are exerted, and the joints simply can’t handle it.

WEIGHT PROBLEMS

Steroid abusers who stop abusing often deal with atrophied muscle mass which converts to fat. Many former abusers report a problem managing weight gain, or losing excess flab and soft tissue that occurs when the muscles are no longer being fed high doses of testosterone. Excess body weight contributes to a host of long-term problems including the aforementioned cardiovascular issues.

NEUROLOGICAL ISSUES

Studies have confirmed steroid abuse has a long term effect on the neurological pathways of the brain. Depending on the age when steroids are taken, the effects can sometimes be permanent. For example, abusing steroids in the teenage years of development has shown to affect the brain’s ability to properly produce serotonin, the enzyme tied with our sense of well-being. This tampering with serotonin can lead to permanent increases in depression and aggression. In women, this hormonal tampering can also lead to significantly lower levels of progesterone and estrogen, potentially upsetting the delicate balance of female chemistry and inducing severe anxiety and depression.

SUMMARY

Though proponents of steroid use may praise the benefits that steroids can have on muscular development and improved athletic performance, any properly informed individual will be hard pressed to deny the possibilities of detrimental side-effects. Coming back to the reasons for steroid abuse, it is understandable that steroid abuse is so rampant considering the powerful influence of the human need to achieve or simply feel better about one’s self. However, even when considering that no side effect is guaranteed to occur, the overwhelming evidence of dangerous side effects should be enough to persuade most people to steer clear of anabolic steroids. Unfortunately, that is not the case. Currently, over 2 million people reportedly abuse steroids in the United States.

Bibliography of Sources: “Anabolic Steroids,” anonymous, CESAR, Center for Substance Abuse Research, 2007 “Anabolic Steroids- Hidden Dangers,” anonymous, Office of Diversion Control, March 2004 “Factors Contributing to the Cause of Acne,” anonymous, Facial Skin Care.com, 2007 “What Causes Prostate Cancer?,” anonymous, eHealthMD, October 2004 “Steroids:Anabolic.Androgenic,” anonymous, Focus Adolescent Services, 2005 “Dr. Delgado’s Gynecomastia FAQ,” Dr. A. Delgado, Gynecomastia.org, January, 2007 “High Blood Pressure FAQ’s,” anonymous, Aetna IntelliHealth, June 10, 2005 “What You Should Know About Steroids,” Steven Dowshen, MD, Miami Children’s Hospital.com, Feb. 2002 “Do Steroids Cause Stunted Growth,” Henry Bernstein, MD, Family Education, 2007 “Big Muscles Now May Mean Big Health Problems Later”, Valerie Gliem, University of Michigan Health System, Aug. 2001 “Anabolic Steroids: A Primer,” William Llewellyn, Muscular Development Magazine, 2006 “What is High Blood Pressure,” anonymous, National Heart and Blood Institute, April 2006 “What are the Health Consequences of Steroid Abuse,” Research Report Series- Anabolic Steroid Abuse, anonymous, National Institute on Drug Abuse, Sep. 2006 “Steroid Use Causes Long Term Aggression,” anonymous, Northeastern University, Nov. 2003 Anabolic Steroids, “Teens At Risk,” NIDA for Teens, 1997-2003 National Institute on Drug Abuse. “Steroid Abuse and Teens,”NIH Pub. No. 00—3721. Bethesda, MD: NIDA, NIH, DHHS. Printed 1991. Reprinted 1994, 1996. Revised April, 2000. Pope, H.G., Jr.; Kouri, E.M.; and Hudson, J.I. Effects of supraphysiologic doses of testosterone on mood and aggression in normal men: A randomized controlled trial. Archives of General Psychiatry 57(2):133-140, 2000. “Anabolic Steroid Abuse,” anonymous, University of New Mexico Student Health Center, 2004 “Steroid Phobia: myth vs. fact’” Andy Nish, MD, Allergy & Asthma Advocate: Summer 2004 “Kids and Steroids,” Dr. Fred Hatfield, Bodybuilding.com, 2006 “Drug Scheduling,” anonymous, U.S. DEA, 2006 “Steroid Medical Realities Outweigh Steroid Myths,” Colin Nelson, MedPage Today, March, 2005 Malarkey, W.B., Strauss, R.H., Leizman, D.J., Liggett, M., Demers, L.M. (1991) Endocrine effects in female weight lifters who self-administer testosterone and anabolic steroids. American Journal of Obstetrics and Gynecology, 165, 1385-1390  Strauss, R.H., Liggett, M.T., Lanese, R.R. (1985) Anabolic steroids use and perceived effects in ten weight-trained women athletes. JAMA, 253, 2871-2873 Psychiatric and Medical Effects of Anabolic-Androgen Steroid Use, Harrison Pope, Jr., and David Katz, Archives of General Psychiatry, May, 1994, pp. 375-82. “More Male than Male,” Etienne Benson, Monitor on Psychology, Vol. 33, No. 9 October 2002

THE USE OF ANABOLIC STEROIDS

Steroids are administered over a period of so-called. cycles, i.e., certain number of weeks and are given equal or greater number of weeks, do not use. The logical approach is required to achieve maximum effect, as well as the maximum health. It is essentially a ‘clean’ androgen receptors in the body to restore natural testosterone production, editing, liver and other organs.

Generally, the period of the AS-cycling should be:
 – rather longer in training volume
 – rather less in speed-power disciplines
 – for beginners rather shorter

It starts at 3 weeks and gradually add to the length, but not more than 8 weeks. In extreme cases, when multiple repeat cycle used 12-week cycles. Longer term continuous administration is particularly effective when the plant which can induce overgrowth of myofibrils, but only in an increase in overall health prevention and control.

 – women rather shorter, probably around 4 weeks (longer application time can induce virilising effects)

The breaks between cycles are:
 – at 3-week cycle pause is about 4-7 weeks, ie about 4-5 cycles per year
 – at 4-6-week cycle is 8 weeks interval, ie about 3-4 cycles per year
 – in the 12-week cycle pause is about 12 weeks, ie about 2 cycles per year

The cycles are practiced in many different ways applications AS:
 – the shooting – a technique “trial and error”
 – mixing – mixing different types of steroids
 – accumulation – more concomitant drugs
 – narrowing – a gradual reduction of income AS deployment preparations to restore natural body functions (Proviron, clomid, HCG)

The inclusion of the very first cycle are generally used smaller doses. Very good results are achieved men at doses of about 10-15 mg / day in the top, the women around 4-5 mg / day. In subsequent cycles, the dose and gradually increase to a current health check (at least liver function tests).

In AS androgen type (ie preparations related to male sex hormones) in general:
 – anabolic effect usually occurs already at a dose of about 2mg / day
 – Men highest effect, when in the cycle average dose of about 30 mg / day, 0.25 to 0.35 mg / kg. When this number is high anabolic effect and quite acceptable health risk in terms of athlete – male.
 – terms virilising risk women would not exceed a dose of 3-5 mg / day for preparations with strong virilizing effects and preparations for that poor virilising may come to the 10-20 mg / day
 – generally single maximum daily dose for men on average for around 0.5 to 1 mg / kg / day in the apex. But here there is no significant health risk.

Higher doses (like those above) produces an anabolic effect only slightly larger. At doses above 1 mg / kg was found to increase the anabolic effect, but very quickly adding health risk and profitability of who the preparation (with recommended treatment group) sold. That’s right: higher doses are not effective, optimum is 30-50mg per day. Use of 700-1200 mg / day is nonsense! This “kamikaze style” only leads to two results:

 – you block intracellular androgen receptors, ie the place where the muscle receives the command for growth 

 – gamble with their own health

In practice, the result is tested with oxymetholone (guaranteed by laboratory analysis) started at 2-5 mg every day and add 2 mg. The peak was at 14 days at 30-35mg. The increase was 7 kg, with creatine supercompensation another 1 kg. Even if you took 1200 mg, have achieved higher growth (in theory you should reach forty times ie 280-320 kg). The result of this test supported the claim that the body probably is not able to absorb more than 300 mg of steroids daily by the oral route. Higher doses need to inject.

When choosing a specimen is taken into account:
 – it is always better combination of several types of products (the lower reaches health risk
     and massive anabolic effect), usually steroids synergize each other. Moreover
     Some steroids probably act on some muscles more than others to
 – strong antigonadotrofíny are classified either cycle or the second (downward)
     half men, if they are used, with a tendency flavored preparations, included in the first
     half cycle. They are then in the middle of the cycle suddenly withdrawn. Conversely, in the  second half of the cycle, flavoring substances shall be included little or no
 – women, when used, preparations with a tendency to virilisation and progestogen is included in the first half cycle. In the second half-cycle of the substance will be used, where these effects are minimized.

The most common dosage of AS converts the total amount received mg weekly. The question of course is how far the recipient is capable of steroids go, so much risk. Because it is clear that the higher the dose taken, the greater risk is issued. Many big guys trying to eliminate harmful effects of deploying more light steroids (such as deca-durabolin, Equipos, Primobolan, oxandrolone). But there are also those who take risks and take more harsh steroids as testosterone esters (anadrol, dianabol).

Anyone can set a weekly dose of 800 mg. If the whole 800 mg taken in the form of testosterone, risking much more harmful effects than if they used the 250 mg of testosterone in combination with 550 mg deca, which is much safer steroid.

About it, how much can a person chooses depends essentially only on the individual’s willingness to take risks. Although it but everyone has to accept some risk associated with different size lots. Quite many beginners tested about 200 mg / week. Achieve much more experienced dose of about 2000 mg / week, ie ten times more. Even some of the names associated with the use of 5000 mg / week, though of course it’s already wasted preparation and finances.

For beginners, it is best effective dose range of 200-400 mg / week. Experienced achieve good results in the 700-900 mg / week. Unfortunately, the side effects of steroids (such as gynaecomastia …) often occur even at 750 mg / week. That does not mean that adverse effects can occur with much smaller doses, but their presence here is not so common.

STEROIDS HALF-LIFE

 

Steroid Half life’s – anyone new to steroids may be wondering what this means, even some steroid users may also be wondering what this means. So here in simple terms you can read and hopefully understand all about steroid half life’s and what this term means. 

Basically every drug has a half life, steroids included. If for example, you were to inject 200mg of Decadurabolin once weekly, for 6 weeks, how would you know when you were “off”? Would you be “off” when you had finished your last dose? You would be able to calculate this from the half life of Deca. The half life of Deca is around 14 days. This means that 14 days from your last shot of 200mg of Deca, your blood levels of Deca will contain 100mg of the steroid. Another 14 days from then, i.e. 28 days from last dose, your blood levels will contain 50mg of the steroid. This amount then keeps halving every 14 days. Therefore you can clearly see that when you finish your cycle, even though you are not putting any steroids into your body, you may think that you are now “off”, however you still have, and will still have for some time after your last dose, “active” blood levels of the steroid. Therefore you can plan what to use, how long for, and how long off your cycle, based on these half life’s.

Below a list of half-life’s of the most commonly used steroids, esters and ancillary compounds.

Steroid Detection and Half-life Times

Steroid Detection Times

For the vast majority of anabolic steroid users, steroid detection times are of no concern; after all, most people are not tested. In the U.S. alone, it is estimated more than six-million adults supplement with anabolic androgenic steroids for the sole purpose of performance enhancement, and of these individuals 85-90% does so for personal reasons. They are not competitive athletes, they don’t play any sport; they are simply everyday people, gym rats who are looking to build a better and healthier body. Of course, for the remaining 10-15%, the steroid detection times can become beyond important; after all, a failed test can result in the end of your sporting pursuit. With this in mind, we want to look at the steroid detection times, but before we dive into the actual times we want to look at all the info you need to know.

The Standard Test

If you are subject to anabolic steroid testing, in most all cases, it will be a test that measures your testosterone to epitestosterone levels. In this case, if your testosterone levels are greater than your epitestosterone levels beyond a certain point, you will fail the test. In most athletic circles, the baseline is 6:1 testosterone:epitestosterone; however, there are a few organizations around the world that hold to a 4:1 ratio.

In-order to beat such testing, you have two options; ensuring the hormones have cleared your system in a way that will ensure your levels are not elevated or skewing the levels. For years, the East Germans masterfully perfected this process by ensuring all their athletes were administered epitestosterone; in doing so, they ensured they stayed within the acceptable 6:1 ratio; their testosterone levels were up, but so were their epitestosterone levels. Then came the late Bay Area Lab Cooperative (BALCO), and they took what the East Germans had done and perfected it even more. Of all the performance enhancing drugs provided by BALCO, none would be more important in-regards to steroid detection times than Tetrahydrogestrinone (THG) which would take the name more commonly known as “The Clear”; it would hold this name due to its undetectable nature despite holding strong Trenbolone like qualities.

At any rate, as for the test itself, the standard test is simply a urinalysis and nothing more. There are hair-follicle test that can be administered; however, most sporting organizations do not perform such test as they have been found to be flawed in numerous ways. In any case, when the athlete understand steroid detection times, if he is aware of when a test may take place, which isn’t that hard to do, he can ensure he passes each and every time.

Choosing the Right Steroids

If you are a tested athlete, if you’re going to supplement with anabolic steroids you must understand steroid detection times thoroughly if you stand a chance. For the tested athlete, you will be somewhat limited in-regards to which steroids you can use. For example, if you’re a truly tested athlete, Nandrolone based steroids can never be used as their detection time stretches past a year. Many testosterone compounds must also be avoided; especially large esters or testosterone mixtures, but the smaller or ester free versions are often an option. Of course, many athletes who are tested are only done so for show, and if that’s the case, well, it really doesn’t matter what you use. In any case, for show or a legitimate test, if you understand steroid detection times there’s really no reason for you to have a problem.

Steroid Detection Time:

Anavar 3 weeks
Anadrol 2 months
Andriol 1 week
Boldenone Undecylenate 4-5 months
Clen 4-5 Days
Deca 18 months
D-Bol 5 weeks
Ephedrin 4-5 days
Halo 2 months
Masteron 3 weeks
Methamphetamin 6-10 Days
Nandrolon Phenylprop 12 months
Primo Depot 4-5 weeks
Proviron 5 weeks
Sustanon 3 months
Tremolon Acet 4-5 weeks
Test cyp 3 months
Test enat 3 months
Testosteron suspension 1-3 days
Test Prop 2-3 weeks
Winny oral 3 weeks
Winny inj 2 months (some say 6 months)

Steroids Half-Life

Oral steroids Drug Active Half-Life 
Anadrol / Anapolan50 (oxymetholone) 8 to 9 hours 
Anavar (oxandrolone) 9 hours 
Dianabol (methandrostenolone, methandienone) 4.5 to 6 hours 
Methyltestosterone 4 days 
Winstrol (stanozolol)
9 hours 
Halotestin (Fluoxymesterone) 9.5 hours 
Turinabol (Tbol) 16 hours 

Injectable Steroids: Drug Active Half-Life 
Deca-durabolin (Nandrolone decanate) 15 days 
Equipoise (Boldenone undecylenate) 14 days 
Finaject (trenbolone acetate) 3 days 
Primobolan (methenolone enanthate) 10.5 days 
Sustanon or Omnadren 15 to 18 days 
Testosterone Cypionate 12 days 
Testosterone Enanthate 10.5 days 
Testosterone Propionate 4.5 days 
Testosterone Suspension 1 day 
Winstrol (stanozolol) 1 day 

Steroid Esters: Drug Active Half-Life 
Formate 1.5 days 
Acetate 3 days 
Propionate 4.5 days 
Phenylpropionate 4.5 days 
Butyrate 6 days 
Valerate 7.5 days 
Hexanoate 9 days 
Caproate 9 days 
Isocaproate 9 days 
Heptanoate 10.5 days 
Enanthate 10.5 days 
Octanoate 12 days 
Cypionate 12 days 
Nonanoate 13.5 days 
Decanoate 15 days 
Undecanoate 16.5 days


Ancillaries: Drug Active Half-Life 

Arimidex 3 days 
Clenbuterol 1.5 days 
Clomid 5 days 
Cytadren 6 hours 
Ephedrine 6 hours 
T3 10 hours 
Letrozole 45 hours 
Nolvadex (Tamoxifen Citrate) 14 days

CHEMISTRY AGAINST FAT

After the publication of the article on muscle definition I got from several readers questions concerning substances used in drawing period, especially those “forbidden”. Most of it was ephedrine, clenbuterol and thyroid hormones (T3, T4), also found no one who was interested in DNP, because it wants to include in your diet supplementation. So I decided to publish the following article page taken from the site Biomag and add some links. So here is the article (quotation marks):
“Today we look at some of the substances that can help you get rid of excess fat. Do not look for them in sports stores, because neither one of them in our country is not allowed and they are all either prescription drugs or substances that would a normal person (IQ> 2) ever made.
Probably disappoint you when I say that the elimination of fat (lipolysis) in the food you take in fewer calories than your body uses. Traditionally, this state is reached by reducing the energy value of food intake, either by changing the food less abundant energy (such as limiting dietary fat), or by reducing the amount of food intake. Another option is to increase the energy requirements of the body. This can be achieved either aerobic exercise or the use of substances accelerating metabolism. And it is for such substances this article. “

EPHEDRINE

“Ephedrine is probably the best known substance for fat loss. In China it is used for at least 2000 years, and its source is a plant Ma Huang. Ephedrine is an alkaloid with thermogenic (heat) and anorectic (appetite potláčajúcimi) effects. Ephedrine is used to treat such as asthma and bronchitis. Ephedrine is not active in fat cells directly but indirectly. After taking the body eliminate noradrenaline and adrenaline. Noradrenaline binds to the alpha and beta receptors on fat and muscle cells. Whereas alpha receptors fall and beta receptors increase lipolysis, the overall effect is then determined by the ratio of the alpha and beta receptors in the adipose tissue. This ratio is different for different body parts and sex. Women have the least favorable ratio of the hips, thighs and buttocks, men in the abdomen and hips. Therefore, in these areas hardly fat removed.

In muscle tissue causes noradrenaline anabolic response. This is very significant because the half-life of ephedrine is only 3-5 hours, but helps to maintain muscle mass during a diet and it is important for us. Shows that the following study. 14 obese women kept the diet for 8 weeks. One group received 3 times daily ephedrine and caffeine, and one placebo. The total weight loss was about the same in both groups, but the group taking ephedrine and caffeine lost weight by 4.5 kg more fat and 2.8 kg less muscle mass.
I do not know of anyone who would use ephedrine alone. Always takes at least with caffeine or with aspirin. Caffeine itself promotes fat loss, accelerates metabolism and has been shown theoretically that significantly increases the effect of ephedrine, although at the same time reduces the effect by reducing the body temperature. In studies obese mice it was found that a combination of aspirin + ephedrine, almost double the efficiency Relative to ephedrine. In the case of humans, however, this effect is not so pronounced and is expressed only in obese humans.

Usually taken 3 times a day 20 mg ephedrine, caffeine 200 mg and 300 mg aspirin. The aspirin can feel left out. We can not buy ephedra legally, in some countries, however, can normally buy at a pharmacy or trade in sports nutrition. Receive either caffeine along with aspirin at a pharmacy called ACYLCOFFIN (not buy one today, but the quality and cost-effective product caffeine can now buy Hungarian tablette caffeine Caffeine (product code 134), which contains 100 mg of pure caffeine in one pill. Aspirin is the same as aspirin, herbal substitute is sold under the name Willow`s bark.

Support for burning fat is not the only effect of ephedrine. The most common side effects include insomnia, nervousness, loss of appetite. Dangerous is mainly palpitations and high blood pressure. People predisposed to such problems should be definitely consult a doctor. Caffeine often causes stomach problems. I personally used to it very badly. Generally after 1 to 2 weeks to get used to and resolve problems.

Ephedrine + caffeine + aspirin I was taking and I was always happy with it. Reduces the loss of muscle mass during diétovania and accelerates the process of fat loss. “

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CLENBUTEROL

“Clenbuterol is used to treat bronchospasm – bronchospasm. It has a similar effect as ephedrine, but acts directly on the beta receptors. Since affect alpha receptors, its effect is much stronger than the effect of ephedrine. On the other hand results in rapid desensitization of beta-2 receptors and approximately 2 weeks expire. Then it is customary to increase the dose, but it only further accelerate the desensitization of beta receptors. Clenbuterol is therefore suitable for short-term treatment, mainly for removing the last remaining fat.

Used is usually 3 times daily, 0.02 mg to 0.05 mg. Initially, it is appropriate to start with smaller doses and gradually revise the specified value. Will limit the side effects of the substance. Because of the long lifetime of the human body clenbuterol used Cycle 1/1 (1 day and giving one day rest period) or 2/2 (2 days to give 2 days and break). Our pharmacies are sold under the name clenbutherol Spiropent and is prescription only.
Side effects are most palpitations, hand tremors and muscle spasms. These usually after a few days of use disappear. However, there may be other problems such as dizziness, nausea, headache, restlessness, abnormal heart rhythm. Clenbuterol should not be used by people with overactive thyroid, accelerated heart activity and heart rhythm disorders.
Clenbuterol has strong anabolic effects in animals. You may have heard about Chinese pigs who discovered the excess concentration. Farmers this substance often used to increase the weight of farmed animals. The man reportedly clenbuterol has anabolic effects. It is only the theoretical hypothesis, based on a lower number of specific receptors in the human body compared to animals. Assess anabolic clenbuterol practical measurements is not possible due to the huge difference between the benefits to be applied in animals (4 mg / kg) to the people (0.04 mg / day).
Clenbutherol is therefore a very powerful tool for getting rid of fat if we are running out of time. It is effective for about two weeks and the results are clearly visible after a few days. In addition, after you use a lot of energy and a feeling that you can more than usual. I personally train with clenbuterol much better than without it. In practice, the better I can concentrate and get to the finish working fairly unpopular and difficult exercises with maximum dedication. I had enough problems with cramps, but it is necessary to just drink lots of water and take multivitamin pills. “

DNP

“DNP (2,4-Dinitrophenol) is a chemical with a variety of applications. DNP already in 1900 detonators used in the TNT ignition. In 1931 Stanford University study showed that it has incredible potential to cause weight loss, so the DNP become the basis of many products for weight loss. Two years later it was banned because of serious risks associated with its use.
Unlike ephedrine and clenbutherol that cause about 3% faster metabolism DNP effect is incredible. This material provides up to 50% increase in basal metabolic rate (BMR basal metabolic rate). DNP has anorexic effects, that reduce appetite. On the contrary, they are often seen bouts of gluttony, especially the need for carbohydrates. DNP affects the process of ATP, the energy source for muscle work. If it is present in the body DNP, reactions that result in the normal state of ATP, producing only heat as DNP prevents the formation of ATP. Resulted in an increase in body temperature usually by 1 to 1.5 ° C Heat is secreted by the entire surface of the body and especially the head.

BUT …

Super potential for fat loss is probably the strongest collection of balanced risks and side effects of what I’ve heard so far.

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– Increase in body temperature is not limited in any way from the top. In overdose, top inside, because there is no body in the protective mechanism against the effects of DNP. Ingestion of 4-to 6-fold dose is lethal. Below overdose can damage the brain and other organs.

– It is assumed that DNP may have carcinogenic effects, that can promote cancer. Moreover, when fast fat oxidation liberates free radicals, and many substances that can also be potentially dangerous.

– Since all the heat generated must somehow get out of the body, so there is a strong sweat even in winter.

– Like other products for weight loss, and insomnia caused by DNP.

-Low levels of ATP, caused by using DNP, causes muscle pain. Is recommended training on 15 or more repetitions of a single sequence, which would alleviate the pain.

DNP has one interesting feature. From just yet unidentified reasons occurring after treatment for about 3 kg gain muscle mass without the use of some other products. DNP is currently the most powerful weapon in the fight against subcutaneous fat. Because of the huge risks associated with the use of this substance DNP definitely not recommend. Think of this part as an informative article and you wait until scientists invent something that will have a similar effect, but not dangerous.

ADVICE FOR GOOD NUTRITION DURING STEROID TREATMENT

Insufficient supply of quality food is often the reason why bodybuilders do not make any visible progress. What is the best use of the training schedule, taking anabolic steroids long enough relaxation time when the body does not have the proper nutrients in sufficient quantity. Intensive trénujúci builder has definitely increased consumption of quality nutrients, which are compounded by Current use of anabolic steroids. Sufficient intake of quality nutrients rapidly increasing effect for each steroid cure because steroids show their full effect only when the body is supplied the necessary amount of calories and the right mix and amount of nutrients. Therefore, we should realize that the correct diet program suitable for this Cieza must meet four basic requirements:

1. Sufficient intake of quality protein.

Receiving quality protein in sufficient quantity plays a crucial role in the process of increasing weight and shipping of quality muscle mass, because proteins are the basic building blocks for muscle tissue. Is also very important source of protein. animal protein in the first place, because it contains protein of high biological value and high content of essential amino acids. Protein body received in the form of food in the body decomposed into amino acids and then transported by the blood to the muscle cells. The main objective is to achieve a positive nitrogen balance in muscle cells, which means that it is assimilated more protein than is released. The best sources of protein are meat (beef, poultry, fish), eggs and dairy products. Required amount of protein depends on the weight of the athlete, but on average ranges from 2 to 3 g protein per kg body weight / day. Higher doses are unnecessary because an unnecessary burden on the digestive tract. Bodybuilder weighing 100 kg, therefore, needs to receive daily 200-350 g protein. Is obvious that such a dose of protein to be broken down into more courses. Since 1 gram of protein has an energy value of 4.1 kcal (calories) should the bodybuilder weighing 100 kg daily take 800 to 1400 kcal in the form of protein.

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2. Sufficient intake of complex carbohydrates.

The importance of complex carbohydrates in the diet of bodybuilders is often emphasized. It certainly does not just happen by accident. Complex carbohydrates provide us with a constant supply of energy, which is very important in maintaining a steady blood sugar level, in order to prevent protein changed into energy (catabolism), and are an important factor in the process of fat loss. The preferred sources of complex carbohydrates are: rice, oatmeal, whole grain bread, pasta and vegetables. The total daily amount of carbohydrate taken should be around 600 to 900 grams, which corresponds (at the energy value of carbohydrates 4.1 calories per gram) daily values of 2400 to 3600 kcal in the form of carbohydrates. 85% of them should be in the form of complex carbohydrates and the remaining 15% in the form of simple carbohydrates, mainly fruit.

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3. Sufficient intake of calories.

Bodybuilder who trains daily and take only 2000 – 3000 calories per day is not even surprised when recording any gains in weight and volume. If you’ve ever seen a massive bodybuilders using steroids during the bulk phase, we certainly agree with you that the day they eat an awful lot – 1/2 kg of meat a bounty of rice, dozens of eggs, vegetables and a few liters of protein and carbohydrate drinks is nothing unusual. If you want to be great, you have to eat a lot – it is a favorite slogan among bodybuilders who understand that diet is 75% of bodybuilding success. If you are healthy, you have a normal metabolism, train hard and regularly, you gain weight and you take anabolic steroids, so surely you closer to your goal if you forget the fact that the caloric intake of about 4000 kcal and more will ensure that you will successfully move forward.

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4. Eating regularly at the same time.

This point is quite often neglected because it requires a high degree of discipline, motivation and long-term planning. I suggest that you join together your diet plan and your daily schedule and passed it without compromise. Eat 7 times a day, or at least 5 – 6, on the same time. It does not matter whether you are hungry or not, whether you are traveling, you’re at work or with friends, at five o’clock you know it’s time for your fifth meal to eat. Regular meals at short intervals (2 -3 hours) will ensure continuous release of insulin, which is important for a fruitful transport of amino acids into the muscle cells and the body as still remains in anabolizme (ideal for scooping the status of matter). Irregular meals, missed meals or a few large meals daily for the bulk phase of your training inadequate. The effectiveness of the system board and outlined the main lines is based on two basic essential requirements: motivation and discipline. This really shows how much you desire to build a large amounts of power, and how much you want to achieve this goal. Those of you who do not have enough motivation and discipline leave the system after a few weeks and will return again to a comfortable eating habits. Bodybuilders with a clear idea of their goals, a great deal of dedication, discipline and a strong psyche survive this mess in the system (although often dull) months and even years. However, it will cost them and reciting the other hand will surely be rewarded.

PROPER PREPARATION TRAINING DURING STEROID TREATMENT

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If you regularly visit one and the same gym and noticed here and there and other people, so you have a longer follow-up will certainly also noticed that most of them still use the same weight and reps. Why? Because a lot of wasted time, wasted bodybuilders still use the same training and the same weight training. If building muscle mass and still be adequately supported by a training deployment, so between us would be much more solid guys.
The truth is that most of the builders wasted create their own obstacles, and yet greatly complicate the feasibility of their goals – building muscle and strength. Most of those who do so “difficult to achieve the objectives”, but with joy-called hardcore bodybuilders. Hardcore is not to train 6 times a week for three hours, or copy-Lee Haney training and preparing for competition, but it’s something else entirely.
Create a sensible training plan and follow it without compromise for a longer period of time is what makes the real-Hardcore bodybuilder hardcore bodybuilders, because only he has the necessary dose of willpower, discipline and perseverance. Forget infinitely long training routines, training programs super winners Mr. Olympia and start to think about the basics, without which a strong and massive muscles could exist.
You should take to heart a few things that are necessary for successful training progress.

What role is played by the use of anabolic steroids?

Very simple: bodybuilders who use steroids will make clearly faster, better and more advanced than their natural counterparts. It also achieved a much higher level of development that would not use steroids achieved.
Quite often, there is the silly god and unfortunately also often proclaimed the view that the same mass and strength achieved by use of steroids can also be obtained with the use of “clean” products, but it takes a little longer. This is not true! There is nothing more ridiculous than absolutely false propaganda that extend people who are in their interests trying to conceal the truth – the authors of books and articles “Stop anabolic steroids.” The following lines read an open mind and try to adapt this information to your personal needs.

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1. High-intensity training (High-intensity training).

The body violently rejects any unnecessary changes if they feel best in a constant shape and balance. To be “pulled” out of his passivity, sometimes you need to practice more than used to. Signal that the body needs to begin to build strength and mass is caused by a mass of hard and intense a training deployment. It may also consist of a few series. 5-8 sets for large muscle games and 3-4 sets for small muscle groups is quite sufficient if each series is carried out until muscle failure. Just take the example of Dorian Yates, who not train more than 30-45 minutes a day and up to 4 times a week and despite the multiple Mr. Olympia. In its bet on training intensity and quality.

2. Train with a relatively small number of repetitions.

The human body has two types of muscle fibers – fast white and slow red. Because muscle hypertrophy is largely influenced by the rapid growth of white muscle fibers, sensible training must be drafted so that it is these muscle fibers are sufficiently stimulated. For this purpose, suitable relatively small number of reps per set. They should be in the range 6-10, depending on the size of the muscle portion. Bigger muscles can withstand even higher loads, so the 10 repetitions in a series of back or leg is sufficient. Of course we must not forget the slow red muscle fibers, which are increasingly burdened mostly higher number of repetitions in the series. Such a series with more reps, we should factor into the workout with some frequency to every 3 to 4 training. This will ensure that both types of muscle fibers are sufficiently loaded.

3. Train with gradually increasing trainings-weights.

In order to achieve muscle growth we must expose them regularly increasing opposition’s training – load. This can be achieved if a bodybuilder workout routine, gradually increase the training weight training. What makes muscles stronger the more they seem. Strength and muscle volumes go hand in hand. It must be remembered that NO FORCE IS MASS. Best for scooping forces are, of course, basic exercises, which is involved in the movement of more muscle groups simultaneously, for example.: Bench press, squat, a pressure head snapped to the trapeze, deadlift, bentover, … etc.
Weight training to increase gradually after 0.25 or 0.5 kg. Maybe you will seem pointless and ridiculous, but precisely for that purpose in the gym are those little wheels. No need to be embarrassed by 0.5 kg attached to the bar. If you imagine that breast exercise 4 times a month, so by adding this 0.5 kg in each year of training you to be able to push a 24 kg more.

4. Long enough post-workout recovery.

The muscles in the gym during a workout just to stimulate growth but the growth itself runs just over rest between workouts. The many, especially young people do not understand, and so we can meet with young boys who want to gain weight, and spend too much time in the gym in the hope that the longer there vagabond, it will be bigger.
Training, the muscle fibers, and it is destroying the resting phase of renewing and building. Generally speaking, the higher the intensity of the workout, the greater the damage to the muscle fibers and thus must not exceed the time for the restoration and completion. When you train with sufficient intensity simply can not train every day. If you train the same muscle group twice a week, it is a high probability that your workouts are not intense enough. Learn to accept rest and recovery as an important part of your training. Every day your training should be balanced day of rest. Bodybuilders, whose main goal is enlarging muscle strength and volume should train every muscle group of high-intensity training every 7-8 days.

5. Phasing and scheduling training.

The body may be subjected to the maximum stress only after some time. If it exceeds, our progress will be stopped and we had such a high intense workout went on, performance would have progressed very slowly, and we began to stagnate in the worst case, our performance may start to decline (overtraining).
To avoid such situation, it is necessary to vary the intensity and volume of training every 12 to 14 weeks. The body in this manner will not have time to get used to one and the same training system and will need to constantly adapt to new forms of load. In this way we can year divided into 3-4 training phase and gradually pass from one to the other. The phases should be put on a certain week – two, pause, and then move to the next phase. At each stage, we should focus on the power, volume, shape and can also include the drawing phase.
The next training program takes into account all the major factors that are necessary for a rapid increase in strength and muscle mass. In combination with high quality and nutritionally balanced diet will significantly increase its effectiveness. Since this is a high-intensity training program, it is not recommended to use natural bodybuilders over a longer period. This training program is meant only as a guide and a bodybuilder because it can change according to their individual needs.

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TOXICITY OF ORAL STEROIDS

That the 17-alpha alkylated steroids are toxic to the liver, is indisputable fact. Surely anyone who has met the steroids, I heard rules like: “There is no need to take more than 50 mg of oxymetholone per day and no more than 4 weeks …”. However, they are similar to the arguments based on truth? On the Internet we can find a lot of studies that confirm this assumption, but also refuted. Let’s look at some of them a little closer …

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If you simply place the vial injecting drunk with testosterone (or some derivative thereof) will be ineffective, because they first pass metabolism will be very effective Uptake and degraded. In order for you to make effective oral steroid form only a small interference in the molecule – bind to steroid string some strong bond that can not be easily removed by liver enzymes. In this way producing the steroid that is effective in the oral form. This adjustment is done mostly at the 17-carbon (used as the first carbon. Methenolone – Primobolan). Editing but it also has one disadvantage: this steroid resistant to degradation becomes toxic to the liver …

According to one study, which examined 131 cases of death from hepatic angiosarcoma (a type of liver cancer), 3.1% of these people had a history of anabolic androgenic steroids, which suggests that these steroids can give rise to malignant tumors of the liver. However, this study does not provide any evidence that it is the steroids were the cause of cancer. Let us remember that if we took 100 random people and see how many of them ever having used anabolic steroids (including when they were steroid-imposed medical treatment in order) the number would be very close to 3 percent. Moreover, there is no study that would prove that some 70’s, the number of deaths rose to hepatic angiosarcoma, while over the same period has risen many times users of anabolic steroids.

Another interesting study 2 describes the formation of multiple adenomas of the liver (small and relatively small number of harmless cysts) in Japanese girl after oxymetholone use in the treatment of aplastic anemia. This could theoretically for those who used oxymetholone mean that they would rather look for something else, but when you look at the study a little more closely, we discover an interesting thing: the girl was diagnosed with aplastic anemia at age 14 and the first changes in the liver were observed after six years of use Oxymetholone 30mg daily! Weighing girls somewhere around 45 kg to a dose of approximately 60 to 80 mg for an adult male – bodybuilder day for 6 years! Compare this with the statement in the first paragraph of this article!

Another study 3 describes the toxicity of various steroids on cell culture of rat liver cells. The following concentrations were used: 1 × 10-8M, 1 x 10-6M, 1 × 10-4M. Several factors were examined cell damage. To change the parameters were only at 17-alkylated steroids, methyltestosterone, stanozolol and oxymetholone and only at a concentration of 1 × 10-4 (which is based on the equivalent steroid dose of 30-40mg per kg). This study reveals two things:

1. Alpha alkylated steroids are hepatotoxic, but only at very high doses.

2. Non alkylated steroids do not have very high concentrations of hepatotoxic effects.

Study 4 examined the effect of 8-week cycle of fluoxymesterone, methylandrostenolone and stanozolol to rats at a dose of 10mg/kg week. For 100-pound man to a dose of 1000 mg weekly (143 mg daily). Half of the rats were exposed to physical strain and half not. They were identified as activity of certain enzymes in the liver cells, but serum (blood) levels of liver enzymes in both groups were in the standard! This means that the dose of 17-alpha alkylated steroids while changing conditions in the activity of some enzymes, but in any case we can not speak of hepatotoxicity in the true sense of the word!

What follows from all this? It is true that the 17-alpha alkylated steroids are hepatotoxic. But it is also true that only in extremely high doses. 5.6 According to other studies, the levels of liver enzymes return to standard within 3 months after planting. And also elevated levels of these enzymes in the cycle may be the source of hard training and not on steroids. Probably hysteria about hazards of these substances is just one of the other myths, which is in this sport more than enough.

This article is for informational purposes only! By this or any other article is not conducive to the use of any prohibited substances, and does not support a potential health problems caused by the use of such substances.

APPLICATION OF ANABOLIC STEROIDS

1. Part: What we need for the application of Anabolic steroids.

It is very important to choose the right “tools” in the application of intramuscular anabolic steroid. The basic components are: syringe and needle. Ideal volume syringe for the application is 2 ml. Can also be greater, if appropriate knife one area more than 2 ml, but in general, this amount is sufficient. Disadvantage larger syringe is that, that it is to handle pretty bad. When selecting a needle on steroids, we must remember that it is very important that the substance through the needle to move smoothly, ie. must be sufficiently thick in order to not block the during application, it would not be too thick, the puncture is not very painful. When you look at the packaging on the back needle – removable side and there you will find information on the thickness and length. It is best to choose a needle just under the criteria as buying needles form “please have 10 blue needles” is also quite clumsy and color can be different for different manufacturers. Show off a little and ask for the professionalism it to the thickness and length – and you’ll have problems after. Well, let’s go back to what the different numbers mean. Usually you will find there are several numbers like. 23 G, Nr. 16, 0.6 x 25 These numbers mean this: 23 G The international thick needle (from the English “gauge”). This “gauge” number represents the diameter needle. What makes this number is smaller, the thicker the needle, and vice versa. The needle of 27 G designation is very thin, while the needle bearing 18 G is thick almost like “cannon”. Thinner needles are used primarily in applications of insulin for diabetics and those thicker especially in blood collection. Picking the needle to this issue is quite awkward, because this issue has not provided information about how long the needle. Nr. 16 Another type of labeling needle thickness. 0.6 x 25 detail clearest we describe two properties needles, 0.6 mm – 25 mm and thickness – the length of the needle. It is according to these numbers, you can easily ask for a pharmacy in such a needle as desired. When you summarize it so, so perfect needle is 0.6 mm thick (22 to 23 G, Nr. 15-16) and 2.5 to 3 cm long (25-30 mm). Thickness 0.6 Needles are not so thick that you have trouble injecting them, while they are thick enough to make them easily passed substance, whether it is oily or aqueous form. Less than 25 mm needles for intramuscular administration really not recommended, because it can happen that the needle does not move a muscle until the end of the subcutaneous tissue and muscle. If steroid applied in this area, it will create a sort of local swelling, which may, in some cases, painful. Key, however, is that the application in this area is 100% effective. So no need to worry about it and instead need to use a long needle to fabric get there, where to get the.

Note:

23 G – The international needle thickness (from the English “gauge”). This “gauge” number represents the diameter needle. What makes this number is smaller, the thicker the needle, and vice versa. The needle of 27 G designation is very thin, while the needle bearing 18 G is thick almost like “cannon”. Thinner needles are used primarily in applications of insulin for diabetics and those thicker especially in blood collection. Picking the needle to this issue is quite awkward, because this issue has not provided information about how long the needle.

Nr. 16 – Another type of labeling needle thickness.

0,6 x 25 – The figure, which we describe both properties clearest needle, 0.6 mm – 25 mm and thickness – length of the needle. It is according to these numbers, you can easily ask for a pharmacy in such a needle as desired.

2. Part: The place where we apply Anabolic steroids.

First of all, forget about the arms, forget triceps, dorsal or pectoral muscles, the only two places you have to be envisaged, the thighs and buttocks. Nothing more! Not that it neišlo elsewhere, but expected to have significantly greater experience and feel in the hand and it is likely at this point you do not have. What is the advantage thighs? First of all, the one that on them without any problems and achieve everything you have full control. Compared with ass also the fact that you have much less chance of it in the fat. Disadvantage? Its internal layout is a little tricky so here is a little more chance to inject something you do not. In addition, some substances a few days after application little hurt, which here has the effect of making you a bit limp. But this is not about anything extreme (although it must be added that there are substances that are not far to the extreme :-), but it will get even later. What is the advantage to applications gluteal muscles (buttocks)? First of all, the one that has a very homogeneous structure, and therefore the chance to stab unpleasant “things” below (but if you are extremely lucky to have a n.ischiadicus wiretapping, and here it is worth it!). Also, the application itself is less painful. Disadvantage, however, that the butt can not all achieved properly and becomes a necessity, be in possession of a loved one, who will help you with that. Someone does anyone have a … If you inject a substance after treatment hurts a little, then compared with the thighs not limp, but sitting on uncomfortable chairs you’ll probably feel a little … but otherwise it’s practice for nearly one and a final decision will be up to you . One thing that is very important and they should not forget it: this is where you need to rotate the application! If you do not, you will be out of oil in situ steroid accumulate and may result abces! Specific locations for the application, you can look at these pictures. The thigh is outside area (no upper which can easily hit-n.femoralis) for butt’s upper outer quarter.    

                           place where we apply anabolic steroids - Steroids4U.eu                   place where we apply anabolic steroids - Steroids4U.eu

             

3. Part: How to apply Anabolic steroids.

1. STEP: For application, choose a place where you in its course no one interfere. If you are in a place where you can surprise someone, you will only unnecessarily nervous and then the application can do stupid things. The selected area can bring everything you need to have it “by hand”. “All the necessary” encompasses the following things: ampule with the substance, originally packed needle (keep them rather more), originally packaged syringe packaging clean handkerchiefs or tampons, disinfect and patch.

2. STEP: Unpack the syringe so that, from the side of rod detach the back and the front of the packaging. Do not put the container completely gone, only approximately half the length.

3. STEP: Unpack the needle. Again Remove the rear and front of the pack again only a little, never the whole length. Needle with plastic cover Do not remove!

4. STEP: Now, hold the syringe, pull the whole package and push it onto the needle. She still wears like plastic cover, as well as his, halfway open container. Syringe must hold for the upper part, in any event, to touch her throat, in any case, that her neck or Never place. If you still accidentally touched, discard it and take another.

5. STEP: Now prepare the ampoule. Here there may be two cases – all-glass ampoule or ampoule with a rubber stopper.

A – In the case of all-glass ampule, you must (unless it is from the manufacturer), the narrowest point drink. This can serve as a nail file. Note that I wrote “drank” and not “overwrites”! Make a small incision is only that you follow these very easier breakage. Many substances have yet to notch himself has. For example, if you find a dot on the ampoule, then place directly below it can be found at its narrowest point cut in the strip around the neck, it is not cut all the way around.

(Just a note even if it is in your vial Winstrol, will probably be in the bottom sediment. Therefore, before you need to break even shake well!)

It now remains only to break the ampoule. Grab the top of one arm and the lower part of the second. In place of the incision is the easiest ampoule breaks, ie. just at that point you have to push.

At this point, you can postpone the ampoule on a flat surface, it is much better but still hold two fingers and those remaining with a syringe needle to prepare. About it but in paragraph 6-A and now we have to look more to the second type of ampoules.

B – If you ampoule with a rubber stopper, then remove this because it is designed to puncture. Here but beware! YOU punctured by a needle other than the one which then makes the application! I do not write “is recommended” or “it would be appropriate,” but “YOU” because if not, blunt needle first and second contaminate it and it is something that you simply, your body can not afford! Continued in Section 6-B.

6. STEP:

A – Now the very stretch of all-glass ampoules. As I said, at this point you have a broken ampoule put either on a flat surface or holding it with two fingers. Remove the top cover from the rest of the injection and the main plastic cover (it is possible, depending on the manufacturer, that it will have slightly rotated). At this point, if you have a bare needle, nothing touching it! If the error Reaching into her or touches the table or clothes, replace it with another. One tip is a question of one crown for potential health problems is definitely worth! With one hand, hold the pill, now, in her second dip needle and piston engine withdraw the entire contents. “All content” I say deliberately, because the glass ampule can not be dosed several times (from the vial with the rubber stopper). Finally, stretch a bit more air, get rid of it but only for a while (STEP 7).

B – Now to the actual stretch of the vial with a rubber stopper. The advantage is that it can remove such as only half the content, and the residue left for another day. The disadvantage is that you need a total of two needles. One is the application of a second to stretch the very substance of the ampoule. As you must first remove the small metal “hatch” from the top of the ampoule. Then grasp the prepared syringe with attached needle and remove it from both packages. Now insert the needle through the rubber stopper and withdraw the required amount of the substance. Again, here at the end stretch a bit of air, but how about the next step.

7. STEP: Now, remove the needle from the vial, and if you puncture the rubber cover or if you craned needle of a different type to use the application, replace the needle. How? First, pull the plunger back a little to get the needle all the content on it, then put the plastic cover and a twist to remove it from the syringe. Paying attention to your hands or anything else touching the neck of the syringe! It now (as described in steps 2-4) attach a new needle.

8. STEP: At this moment expel the air from the syringe so to put it in position pointing upwards, and slowly pushing the plunger until the needle appears the hill drop of liquid. If you remain bubbles in the syringe, you can do it gently knock. However, there may not be a stickler too, because a few of balls in the air muscle does not do anything wrong.

Then place the entire syringe plunger on a flat surface such as a desk or hold it in one hand (by the way, now the needle should not slip cover!), Meanwhile disinfect second place for the application. In practice, just sprayed the place as already mentioned SEPTONEX a freshly unpacked paper towel and wipe lightly wipe (not necessary). During this “operation” pay close attention to the syringe needle. It may not be anything to touch! Unless delayed by hand, then place it on a flat surface and place it by mistake disagreement. If capsizes and crashes, you have to replace the needle!

9. STEP: Now, prepare one or two handkerchiefs to be at hand and game, in which you apply, most release. Unless you keep clenched, unnecessarily increase the pain. Hold the syringe, zoom it to the point of application in a continuous motion-insert it into the muscle. The worst part is the piercing of the skin. If you’re afraid and you print very little, you will be the very first puncture a little hurt. However, three images continuously and needle punctures the skin, often not even feel a thing. There is nothing to worry about, whether fast or slow, yet it pierced once, so why add to the pain? Once you pass through the skin, go to the required depth. Required depth is third needle, but its almost full length! It is much less evil to go “to the bone” (it will happen soon anyway), how to apply grease or only slightly below the muscle fascia! Speed of movement still keep flowing if you go too slowly, you will feel that it always seems to stop something from it and generally not feeling well. Faster flowing movement is clearly better.

The moment you are in the required depth, you have to load the piston back piece, if you’re not in the vein. This must never, under any circumstances, forget it if you would send oil substance directly into a vein, you could stay only a few seconds of life! Back strain will not go very well, with one hand hold the syringe and the other a little pull. If you see air bubble, everything is fine. But if you see blood, stop stretching a one-handed grab in peace handkerchiefs ready. Now attach them around the needle, slightly pinch it and flick the other hand, remove the needle. At this point, tissues press on the place and moment to Remain. This will sooner or later likely to happen, it just keep cool and do not panic! If at the moment you notice blood, violently pulling needle, you have a decent likelihood that it will be followed by a spurt of blood. However, by attaching strong enough tissue, except for a small bruises all will be safe and sound. Now you have to apply elsewhere. If during this event needle touched something which was not, it must be replaced! It is also appropriate to print some blood that will probably be on the syringe.

10. STEP: If but only appeared in the syringe air bubbles, you can gently pushing the plunger to begin to apply. How fast? Generally indicates that the application of 1 ml of the substance should take about 10-20 seconds, though it will be slower, nothing happens. If you use thinner needles will not go even faster, as well as some of the substances in faster application little hurt. With that “slowness” but again, do not overdo it, because after a few tens of seconds you should start to shake hand and especially, you inadvertently move the needle in the muscle, so you can literally cut through the muscle fibers. The result would then be sore for a few minutes or hours after application.

11. STEP: The moment you are with the syringe plunger to the bottom, hold in one hand a paper towel, apply it and remove the needle. It may appear a few drops of blood, but also can not. Tissue can be the place for a few minutes gently massage it to improve the spread of the substance in the muscle and its subsequent absorption, and then you can sealed with prepared dressing. The patch is not required, even for the surroundings to your unnecessarily provocative, if you would but as soon as the application wanted to put on some clothes, any drop of blood would be noticeable too. After a few minutes, but no longer safe.

Only further note: after removing the needle of a syringe you can see a few drops of blood. At this point, you worry if you accidentally inject a vein, but know that at the bottom of the drop is completely normal and does not mean anything bad.

12. STEP: Now insert the needle back into the plastic casing with a syringe, ampoules and other things safely discarded.

VIDEO TIPS:

How to use subcutaneous injection – Steroids4U.eu

How to use intramuscular injection – Steroids4U.eu

WHAT ARE PEPTIDES?

DEFINITION AND SIDE EFFECTS OF GHRP PEPTIDES

SOLUBILITY OF THE PEPTIDES

DOSAGE AND COMBINED GHRP AND GHRH PEPTIDES

RECONSTITUTION, CALCULATED DOSE AND APPLICATION PEPTIDES

STORAGE PEPTIDES

WHERE CAN I BUY PEPTIDES

PEPTIDES CYCLE FOR MEN

PCT (Post Cycle Therapy)

The Perfect Post Cycle Therapy

 

Introduction:

I’ve been writing about the perfect PCT stack for a while, and it seems a lot of guys still have questions about the way to run the right kind of PCT. The perfect PCT is not just an idea or concept or a medical study, it’s something you have to develop with countless years of trial and error. I have written thousands of PCT regiments over the last 20+ years in the industry, and I can safely say that PCT is tricky at best.

History:

Back in the day, most of the gym ‘buff’ bodybuilders didn’t run any PCT. They just kept cycling non-stop. Many had serious health problems and side-effects from it. From liver damage, to heart problems to testicular atrophy. Constantly being on a cycle is risky at best and very dangerous at the least. You’ll see some “broscience” guys coming around B.Sing like they know it all about PCT when they themselves are cycling year round!

What makes a perfect PCT? (Summary)

1) Start-up your HPTA

2) Prevent Catabolism

3) Prevent Fat-Gains

4) Prevent Strength loss

5) Balance Hormone levels

6) Reduce Side-effects

What products do you need to address each of those problems?

1) Starting-up your HPTA: Use a SERM combination, with Clomid and Nolvadex. This will help restart your HPTA.

Let’s look at the science behind this:

*********************************************************************

Int J Impot Res. 2003 Jun;15(3):156-65.

Clomiphene increases free testosterone levels in men with both secondary hypogonadism and erectile dysfunction: who does and does not benefit?

Guay AT, Jacobson J, Perez JB, Hodge MB, Velasquez E.

For those with lower than normal age-matched levels of testosterone treatment directed at normalizing testosterone with clomiphene citrate is a viable alternative to giving androgen supplements.

*********************************************************************

J Sex Med. 2013 Jun;10(6):1628-35. doi: 10.1111/jsm.12116. Epub 2013 Mar 26.

Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel.

Kaminetsky J, Werner M, Fontenot G, Wiehle RD.

CONCLUSIONS:

Enclomiphene citrate increased testosterone and sperm counts. Concomitant changes in LH and FSH suggest normalization of endogenous testosterone production and restoration of sperm counts through the hypothalamic-pituitary-testicular axis.

*********************************************************************

2) Prevent Catabolism + 4) Prevent Strength loss: The use of a powerful SARM Ostarine (MK-2866) to lower cortisol levels and increase your IGF-1 levels. Use salbutamol no clenbuterol. Salbutamol is anticatabolic. Vitaminc C 3-5g per day is very good like anticatabolic supplement.

3) Prevent Fat-Gains: Pick up a bottle of Cardarine (GW-501516), it will help with preventing your fat gains while increasing your endurance. This is the most typical use for Cardarine.

5) Balancing Hormone levels: To prevent estrogen levels from increasing and IGF from decreasing, add Aromasin. To increase you testicle size and boost recovery time, add HCGenerate ES as a PCT kick-start.

6) Decrease Side-Effects: To make sure your kidneys, organs and liver aren’t damaged during your PCT, adding N2Guard is optimal.

***The Perfect 5 Week PCT Laid-Out***

Week 1-2: 2 Week Pre-PCT Kickstart

HCGenerate ES (5 caps/day) – 2 caps AM/1 post workout/1 PM

Cardarine (GW-501516) – 20mgs/day (10mgs AM/10mgs PM)

Week 3-7: 5 Week PCT

Clomid – 50/50/25/25/12.5

Nolvadex – 40/20/20/20/10

Aromasin – week 1-2: 12.5mgs EOD, week 3-4: 7.5mgs EOD

Salbutamol – 16mg per day in four doses

Cardarine (GW-501516) – 20mgs/day (10mgs AM/10mgs PM)

Ostarine (MK-2866) – 25/25/25/12.5

N2Guard or Liver Aid Lagosa – 2 caps AM/2 post workout/3 PM

NOTE: Dosages are PER DAY, example Clomid 50/50/25/25/12.5, means Week 1 you take 50mgs/day, Week 2 50mgs/day and so on. 

WeekHCGenearte ES

Cardarine

GW-501516

ClomidNolvadexAromasin

Ostarine

MK-2866

N2Guard
15 caps/ED20mgs/ED     
25 caps/ED20mgs/ED     
3 20mgs/ED

50mgs/

ED

40mgs/

ED

12.5mgs/

EOD

25mgs/

ED

7 caps/

ED

4 20mgs/ED

50mgs/

ED

20mgs/

ED

12.5mgs/

EOD

25mgs/

ED

7 caps/

ED

5 20mgs/ED

25mgs/

ED

20mgs/

ED

7.5mgs/

EOD

25mgs/

ED

7 caps/

ED

6 20mgs/ED

25mgs/

ED

20mgs/

ED

7.5mgs/

EOD

12.5mgs/

ED

7 caps/

ED

7 20mgs/ED

12.5mgs/

ED

10mgs/

ED

  

7 caps/

ED

NOTES:

ED = every day

EOD = every other day

mgs = milligrams

caps = capsules

What our team recommend in PCT?

1. First week in PCT don’t do workout or cardio. You have a lot of cortisol in body. Your body must rest.

2. After one week of rest train easy with high reps (12-20). Best workout is Full body training or easy split.

3. Eat only high quality meals with high proteins, complex carbohydrates and good fat.

4. Use dietary supplements like BCAA’s, L-Glutamin, L-Arginin and other Aminos, 3-5g of Vitamin C per day, Multivitamin complex, Multimineral complex, Zinc, Magnesium, Antioxidants like Vitamin E, B-complex

5. Use legal Testosteron booster like Tribulus terrestris about 5g per day in three doses AM, post workout and before bed, etc.

6. If you have use Proviron or HCG contact us for doses.

Conclusion

Most bodybuilders and gym-lovers who use or dabble with anabolic steroids forget the importance of PCT and cycling off.  It’s crucial that you take time off your cycle and fully recover.  It’s ironic that guys are spending thousands on their steroid cycles, while they refuse to spend the same on their health.  PCT and recovery = health.  If you never recover, you risk being completely impotent and run the serious potential of ruining your life.  Always remember, health comes first, as you will not be able to buy your health back 10 years down the line; once it’s gone, it’s gone.  Therefore, a proper PCT is crucial for maintaining the homeostasis in your body and boosting your health levels.  Remember, you can use steroids and stay healthy, just don’t ABUSE them.

Nolvadex, Clomid and HCG in Post Cycle Therapy (PCT)

 

WHY BODYBUILDERS USE CLOMID

Clomid is a generic name for Clomiphene Citrate and is a synthetic oestrogen. It is prescribed medically to aid ovulation in low fertility females. Another generic name is Serophene.

Most anabolic steroids, especially the androgens, cause inhibition of the body’s own testosterone production. When a bodybuilder comes off a steroid cycle, natural testosterone production is zero and the levels of the steroids taken in the blood are diminishing. This leaves the ratios of catabolic : anabolic hormones in the blood high, hence the body is in a state of catabolism, and, as a result, much of the muscle tissue that was gained on the cycle is now going to be lost.

Clomid stimulates the hypothalamus to, in turn stimulant the anterior pituitary gland (aka hypophysis) to release gonadotrophic hormones. The gonadotrophic hormones are follicle stimulating hormone (FSH) and luteinizing hormone (LH – aka interstitial cell stimulating hormone (ICSH)). FSH stimulates the testes to produce more testosterone, and LH stimulates them to secrete more testosterone. This feedback mechanism is known as the hypothalamic-pituitary-testes axis (HPTA), and results in an increase of the body’s own testosterone production and blood levels rise, to, in part, compensate for the diminishing levels of exogenous steroids. This is vital to minimise post cycle muscle losses.

Not all steroids do cause shut down of the feedback mechanism. Everyone is different and you must also take into account how long you have been using a certain steroid and at what dose in order to determine if you need Clomid or not.

Clomid also works as an anti-oestrogen. As it’s a weak synthetic oestrogen, it binds to oestrogen receptors on cells blocking them to oestrogen in the blood. This minimises the negative effects like gynecomastia and water retention that may be a result of oestrogen that has aromatised from testosterone.

It’s effect as an anti-oestrogen are quite weak though, and it should not be relied upon if you are going to be using androgenic steroids that aromatise at a rapid rate, or if you are pre-disposed to gynecomastia. Arimidex and Nolvadex (Tamoxifen) are far more effective anti-oestrogens.

Important note: Clomid does not, as is often thought, stimulate the release of natural testosterone, but rather works at reducing the oestrogenic inhibition caused by the steroid cycle. It does this in a similar manner to the way it and Nolvadex block oestrogen receptors in nipples to combat gyno development, i.e. by blocking the oestrogen receptors in the hypothalamus and pituitary thus reducing the inhibition from the elevated oestrogen. This allows LH levels to return to normal, or even above normal levels, and in turn, natural testosterone levels to also normalise.

Inhibition of the HPTA is caused by either elevated androgen, oestrogen or progesterone levels. On cessation of the steroid cycle, androgen levels begin to fall and Clomid dosing is normally commenced according to the half-life of the longest acting drug in the system (see below).

This may also explain the reason individuals often find post-deca recovery more difficult, as the progesterone presence is untouched by the Clomid. We know that Clomid and Nolvadex (being very similar chemically) are both ineffective with regard to reducing progesterone related gyno, so it is reasonable to assume that Clomid has little effect against progesterone levels.

 

Clomid During A Cycle

When we use anabolic steroids, the level of androgens in the body rises causing the androgen receptors to become more highly activated, and through the HPTA, a signal tells our testes to stop producing testosterone. During a cycle the body has far higher than normal levels of androgens and, as long as this level is high enough, Clomid will not help to keep natural testosterone production up. It will be almost all but completely shut off, in theory.

Some heavy androgen users, however, do advocate a small burst of Clomid mid-cycle, though it must be hard for them to say if it really of any benefit, due to the amount of gear they are using. Therefore, the only purpose of Clomid during a cycle is as an anti-estrogen.

When To Take Clomid

The correct time to commence Clomid depends on the type and cycle of steroids you have been using. Different steroids have different half-lifes (indicates the time a substance diminishes in blood), and Clomid administration should be taken accordingly.

As we have seen above, Clomid taken when androgen levels in our blood are still high will be a waste. It is crucial to wait for androgen levels to fall before implementing our Clomid therapy. However, if taken too late we could possibly lose gains.

The list below determines when you should start Clomid. Select from the list any steroids you’ve used in your cycle and whichever one has the latest starting point is the time to commence Clomid. For example, if Dianabol, Sustanon and Winstrol were cycled, the time for administering Clomid should be 3 weeks post cycle, as Sustanon remains active in the body for the longest period of time.

 
SteroidTime after
last administration
 Length of
Clomid Cycle
Anadrol50/Anapolan50:8 – 12 hours 3 weeks
Deca durabolan:3 weeks 4 weeks
Dianabol:4 – 8 hours 3 weeks
Equipoise:17 – 21 days 3 weeks
Finajet/Trenbolone:3 days 3 weeks
Primabolan depot:10 – 14 days 2 weeks
Sustanon:3 weeks 3 weeks
Testosterone Cypionate:2 weeks 3 weeks
Testosterone Enanthate/Testaviron:2 weeks 3 weeks
Testosterone Propionate:3 days 3 weeks
Testosterone Suspension:4 – 8 hours 2-3 weeks
Winstrol8 – 12 hours 2-3 weeks

 

How To Take Clomid

Clomid has a long half-life (possibly 5 days), so there is no need to split up doses throughout the day. If Sustanon has been used and Clomid is commenced 3 weeks after the last injection, I would estimate that androgen levels are low enough to start sending the correct signals. If androgen levels are still a little high, we need to start at a high enough amount that will work or help, even if androgen levels are still a little high. Try 300mg on day 1; then use 100mg for the next 10 days; followed by 50mg for 10 days.

 

HOW TO TAKE NOLVADEX FOR PCT

As an alternative to Clomid, which has been reported to have led to unwanted side effects such as visual disturbances in some users, Nolvadex can be employed. Nolvadex is a trade name for the drug Tamoxifen. Like Clomid, the half life of Nolvadex is relatively long enabling the user to implement a single daily dosing schedule. Administration would start as per the timescales outlined above and the duration would be identical to that of Clomid.

Typically, for a moderate-heavy cycle, the following dosages would be used: 
Day 1 – 100mg
Following 10 days – 60mg
Following 10 days – 40mg

Occasionally, heavier cycles containing perhaps Nandrolone (Deca) or Trenbolone which by definition are particularly suppressive of the HPTA, may require a slightly longer therapy. Likewise, more modest/shorter cycles may require lower dosages, perhaps dropping each by 20mg per day.

Some users like to use both Clomid and Nolvadex in their PCT in an attempt to cover all angles. An example of the dosages involved might be:

Day 1 – Clomid 200mg + Nolvadex 40mg 
Following 10 days – Clomid 50mg + Nolvadex 20mg 
Following 10 days – Clomid 50mg or Nolvadex 20mg

Of course, the examples provided are not set in stone and may be adjusted depending on the factors outlined above and individual variances.

 

Using HCG

It is our opinion that HCG is probably one of the most misunderstood and misused compounds in bodybuilding. Hopefully this information will go some way towards rectifying that for the members of MuscleTalk. HCG stands for Human Chorionic Gonadotrophin and is not a steroid, but a natural peptide hormone which develops in the placenta of pregnant women during pregnancy to controls the mother’s hormones. (Incidentally, this is the reason you may hear of people testing for growth hormone (HGH) with a pregnancy testing kit – If their HGH shows ‘pregnant’, they’ve been ripped-off with cheaper HCG – but we digress slightly).

Its action in the male body is like that of LH, stimulating the Leydig cells in the testes to produce testosterone even in the absence of endogenous LH. HCG is therefore used during longer or heavier steroid cycles to maintain testicular size and condition, or to bring atrophied (shrunken) testicles back up to their original condition in preparation for post-cycle Clomid therapy. This process is necessary because atrophied testicles produce reduced levels of natural testosterone, this situation should be rectified prior to post-cycle Clomid therapy.

HCG administration post-cycle is common practice among bodybuilders in the belief that it will aid the natural testosterone recovery, but this theory is unfounded and also counterproductive. The rapid rise in both testosterone, and thus oestrogen due to aromatisation, from the administration of HCG causes further inhibition of the HPTA (Hypothalamic/Pituitary/Testicular Axis – feedback loop discussed above); this actually worsens the recovery situation. HCG does not restore the natural testosterone production.

The typically observed dosing of 2000 to 5000IU every 4 to 5 days causes such an increase in oestrogen levels via aromatisation of the natural testosterone that this has been responsible for many cases of gynecomastia.

From the above discussion it is clear that HCG is best used during a cycle, either to:

1) Avoid testicular atrophy, or
2) Rectify the problem of an existing testicular atrophy.

HCG Dosage

Smaller doses, more frequently during a cycle will give best overall results with least unwanted side effects. Somewhere between 500IU and 1000IU per day would be best over about a two-week period. These doses are sufficient to avoid/rectify testicular atrophy without increasing oestrogen levels too dramatically and risking gynecomastia. This dosing schedule also avoids the risk of permanently down-regulating the LH receptors in the testes.

It is important for the HCG administration to have been completed with 6 or 7 clear days before the onset of PCT in order to avoid inhibition of the Nolvadex and/or Clomid therapy. Also, a small daily dose (10-20mg) of Nolvadex would normally be used in conjunction with HCG in order to prevent oestrogenic symptoms caused by sudden increases in aromatisation.

Presentation and Administration of HCG

Synthetic HCG is often known as Pregnyl (generic name) and is available in 2500iu and 5000iu (not ideal for the above doses!). Administration of the compound is either by intra-muscular or subcutaneous injection. It comes as a powder which needs to be mixed with the sterile water. The powder is temperature-sensitive prior to mixing and should not be exposed to direct heat. After mixing, it should be kept refrigerated and used within a few weeks – though there are sterility issues which need to be considered after mixing.

SUMMARY AND PRESENTATION OF CLOMID AND HCG

Clomid and/or Nolvadex are more effective than HCG post cycle, but some long-term users like to use HCG during a cycle, or to prepare the testes for Clomid and/or Nolvadex therapy.

Clomid is available in 50mg tablets most commonly, but also comes in 25mg capsule, often in boxes of 24 tablets. Tamoxifen is made by a number of manufacturers and comes in 10mg or 20mg tablets, most commonly 30 x 20mg tablets. HCG generally comes in kits of three ampoules of powder needing to be mixed with the provided injectable water as 1500IU, 2500IU or 5000IU per ampoule kits.

 

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